Execution phase - XNAT

During this step the images are uploaded by the participating sites in the XNAT Project

Images should be uploaded via the CTP software installed in the participating site, which is managed by local IT of the participating site.

Initially, the predefined de-identification profile will be used to upload the images to XNAT.

New users for the study can then be requested by the PI or delegate from the study by filling the "XNAT New User request" request form available in the TraIT Self Service Desk.

There are different user roles within XNAT. The roles at study level are:

• Owner - Full Access
• Member - Full access except deleting
• Collaborator - Only read access

For custom access rights per sight ask the TraIT Service Desk.

Next step: Manage Study

Back to: Execution Phase overview

The study coordinator is responsible for the management of the XNAT project during the execution phase.

The tasks for this person includes amongst others the following:

-       Monitor the usability of the uploaded images for the envisaged research purposes

-       Modify the de-identification profile when required

To avoid late stage problems it is very important to test changes of an ongoing study (e.g. modifications of the de-identification profile). When testing is neglected, it could cause serious problems after years of data collection!

XNAT allows for more than just archiving, viewing and downloading of images. Through the REST API additional functionality can be implemented allowing for more advanced analysis of the data, as well as adding additional meta-data to your project. Read more on the BBMRI website on examples of extended use of XNAT.

Next steps: Interim analysis

Previous step: Uploading images

It is common practice for clinical trials to include a plan for interim analyses of the data, and to monitor safety.

During execution phase, we would advise to perform interim analyses. These analyses assess the quality and format of the data collected.

If you want to perform an interim analysis you need to export data from XNAT, as done in the data extraction step in the completion phase.

Next: Completion phase

Previous: Manage Study