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Dutch biobanking protocol

Project overview

Harmonizing the collection and storage of biomaterials is of crucial importance for the optimal use of biomaterials for health research (e.g., Freedman et al, PLoS Biology 2015). It facilitates collaboration between research groups, increases research quality, and is part of a solid basis for building and maintaining a national health data infrastructure. There is a biobanking protocol available (in Dutch), developed by Parelsnoer, describing nationally agreed minimal requirements for biomaterial collection and storage. However, with the arrival of ‘omics-techniques’, new diagnostic techniques, such as the measurement of cell-free DNA (cfDNA), and the advancements made in cellular analysis techniques, the standard needs to be updated. The project aims at developing fit-for-purpose, evidence-based standards for the collection, pre-analysis, and storage of biomaterials and FAIR registration of (meta)data for biobanking purposes. The project has started with the creation of standards for cfDNA and genomic DNA and will be extended to other material types in the future. A further aim is the creation of awareness for the importance of pre-analytic standardization and of a collective responsibility within the work field for the implementation of the national standards.

Key deliverables

  • A recommendation for the reporting of pre-analytic variables (2024)
  • Evidence-based, fit-for-purpose biobanking standard for pre-analysis
  • Awareness for the importance of pre-analytic standardization
  • Collective responsibility for the implementation of the national standards

Project duration

Ongoing 

Key facts

  • Pre-analysis of Biobanked biomaterials
  • Evidence-based, fit-for-purpose

Organizations

Erasmus MC, Radboudumc,  Amsterdam UMC

Project Team

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